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br Rationale Recently we have shown that the nasal CysLT
2020-08-05

Rationale Recently we have shown that the nasal CysLT2 receptor localized exclusively in blood vessels and the expression level of the CysLT2 receptor in patients with nasal allergy was higher than that in patients with non-allergic rhinitis (Shirasaki et al. Allergol Int 2013). We hypothesized t
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The ketogenic diet has modest efficacy in
2020-08-05

The ketogenic diet has modest efficacy in treating epilepsy in CDD. The largest cohort reported 104 individuals with CDD treated with median ketogenic diet duration of 17 months and reductions in seizure frequency in 61 of 104 (58.7%) individuals, consistent with data from the Boston Children\'s Hos
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Blood serum and plasma contain a range of
2020-08-05

Blood serum and plasma contain a range of enzymes that could potentially catalyze the hydrolysis of urea derivatives. Therefore it is possible for the prodrugs to be prematurely hydrolyzed by the plasma enzymes leading to the release of triazenes before reaching the pre-localized CPG2. Consequently,
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br Conclusion To our knowledge this study
2020-08-05

Conclusion To our knowledge, this study is the first to give evidence that the ETA selective antagonist BQ-123 reverses the cisplatin-induced ARF mainly via restoring SOD activity, in addition to other antioxidant parameters, NO, TNF-α and caspase-3 levels. And that this protective effect require
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br BP targets Two distinct BP targets namely
2020-08-05

BP targets Two distinct BP targets, namely 140/90mmHg in low-moderate risk hypertensives and different clinical characteristics: low-moderate cardiovascular risk (class I, level B), s7694 synthesis (class I, level A), previous stroke or ischemic transient attack, coronary heart disease, chronic
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Although IGF upregulation was not sufficient
2020-08-05

Although IGF-1 upregulation was not sufficient to transform MPC in our model of ESFT, it is likely to be one of several factors directly or indirectly induced by EWS-FLI-1 that are implicated in MPC transformation and tumorigenicity. It is noteworthy that the age associated with the peak incidence o
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br TRIM RNF TRIM also known as Ring finger characteristicall
2020-08-05

TRIM8 (RNF27) TRIM8, also known as Ring finger 27, characteristically contains both B-boxes while lacks any C-terminal domain (Fig. 3). Recently, Chen et al., (2017) have found upregulation of TRIM8 in human dilated cardiomyopathy patients and hypertrophied mice [67]. TRIM8-deficient mice amelior
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Materials and methods br Results and discussion
2020-08-04

Materials and methods Results and discussion Conclusions Clitocypin is another member of the mycocypin family of cysteine protease inhibitors that is unique to 9508 shown to exhibit strong insecticidal activity against Colorado potato beetle larvae. This effect is concentration dependent and
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High density of CRF containing terminals
2020-08-04

High density of CRF-containing terminals, arising mainly from the central nucleus of the amygdala [20], [21], and moderate to dense Ucn1- and Ucn3-immunoreactive fibers [22], [23] were found within BNST. Also, populations of CRF- and Ucn3-containing neurons have been identified in the BNST [23], [24
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The CRF receptor binding affinities for the described compou
2020-08-04

The CRF receptor binding affinities for the described compounds are shown in . Compounds were tested in a CRF receptor binding titration assay using rat frontal selective serotonin reuptake inhibitors homogenate, in which inhibition of specific binding of [I]Tyr-ovine CRF by our test compounds was m
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Whether a school is private or
2020-08-04

Whether a school is private or public may also be an indicator of its quality. In general, private schools have smaller class sizes which may provide a better learning environment. Lindquist and Smith (2013) state that smaller class sizes provide more opportunities for students to interact with prof
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The Czech Republic participated in
2020-08-04

The Czech Republic participated in the European Clostridium difficile infection surveillance Network (ECDIS-net), a European Centre for Disease Prevention and Control (ECDC) supported project that started in 2011 and focused on building laboratory capacity for pan-European Clostridium difficile infe
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br Discussion The use of co
2020-08-04

Discussion The use of co-translational incorporation during fermentation [27] to introduce Hyp residues instead of Pro residues in a bacterial collagen has been demonstrated. Inclusion of NaCl in the medium further increases the level of Hyp incorporation. It has been proposed [27] that this is d
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The Pacific cup oyster genus Saccostrea has been used in
2020-08-04

The Pacific cup oyster, genus Saccostrea, has been used in Australia and Asia as a sentinel bivalve for pollution monitoring, particularly of metals (Barua et al., 2011, Thompson et al., 2011, Thompson et al., 2012a, Thompson et al., 2012b, Andrew-Priestley et al., 2012, Taylor et al., 2013, Taylor
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The Fontan circulation When first described in the
2020-08-04

The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital hydralazine hcl australia disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, which crea
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