• caspofungin br Introduction Bone marrow fibrosis is

  2019-05-24

  

  Introduction Bone marrow fibrosis is known to occur in several neoplastic and non-neoplastic conditions. Among neoplastic conditions such as acute leukemia, it is most often seen with acute megakaryoblastic leukemia [1]. Acute promyelocytic leukemia (APL) presenting with marrow fibrosis is a rare

• Introduction Acute myeloid leukemia AML is a rare disease af

  2019-05-24

  

  Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati

• br Discussion There is an important need for new treatment

  2019-05-24

  

  Discussion There is an important need for new treatment options for AML in elderly patients. Their frailty imposes limitations upon the aggressiveness of the treatment which can be administered [6,24]. In addition, the poor prognostic disease features often seen in this oxyntomodulin mean that re

• HLA DR resulted highly expressed in

  2019-05-24

  

  HLA-DR resulted highly expressed in the surface of immature DC (iDC) as well as in mature DC (48 h-DC) in both groups; this is possibly due to the chronic infection as previously observed in monocytes-derived DC from HIV+[17]. As expected, maturation and activation markers - CD40, CD80, CD83 and CD8

• Pain flare defined as a temporary worsening of bone pain

  2019-05-23

  

  Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte

• Por sua vez na Nicar gua

  2019-05-23

  

  Por sua vez, na Nicarágua, Go 6983 Revolução Sandinista de 1979 foi resultado de um acúmulo de forças sociais heterogêneas –camponeses, operários, pobres e marginalizados da cidade e do campo, intelectuais e setores progressistas da burguesia– em torno de um objetivo comum: liquidar o governo da fa

• One of the unheralded developments in global health

  2019-05-23

  

  One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.

• Juan Tovar dramaturgo y cr tico teatral presenta en

  2019-05-23

  

  Juan Tovar, dramaturgo y crítico teatral presenta en su texto “Los siete géneros”, la teoría que aprendió durante su paso por las aulas de la maestra Luisa Josefina Hernández y cuyas lecciones no obstante su continuo estudio y aplicación por directores y actores en talleres y escuelas de teatro, no

• The occurrence of RNRVAS first reported as

  2019-05-23

  

  The occurrence of RNRVAS, first reported as an isolated case in 1985 [16], have since been confirmed in dual-chamber pacemaker recipients undergoing 24-h ambulatory electrocardiograms, who report symptoms similar to those of patients suffering from pacemaker syndrome [17,18]. Incidence of RNRVAS

• br Introduction Despite the widespread

  2019-05-23

  

  Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested

• Worldwide there are an estimated

  2019-05-23

  

  Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,

• Since the progressive introduction of the

  2019-05-22

  

  Since the progressive introduction of the meningococcal serogroup A conjugate vaccine in meningitis belt countries via mass vaccination campaigns of 1–29 year olds starting in 2010, a remarkable effect of the vaccine has been observed. Similar to other conjugate vaccines, MenAfriVac has demonstrated

• br Conclusions br Disclosures br Introduction Since their in

  2019-05-22

  

  Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging

• br Conclusion br Conflict of

  2019-05-22

  

  Conclusion Conflict of interest Introduction Radiofrequency catheter ablation has been established as an effective and curative therapy for Wolff-Parkinson-White Syndrome [1–4]. Therefore, prediction of the precise location of an accessory pathway (AP) prior to the ablation procedure is of

• br Conflict of interest br Acknowledgments br

  2019-05-22

  

  Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide Senexin B pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome expres

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