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The PAX gene encodes a
2019-06-10
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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To facilitate WHO s goals it is important to assess
2019-06-10
To facilitate WHO\'s goals, it Myriocin is important to assess the cost-effectiveness of interventions that incorporate emerging technologies for case detection, treatment, and vector control in the context of economic constraints and logistical barriers. In an elegant modelling study in , Simone S
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In summary programmed long AVD prolonged VA conduction
2019-06-10
In summary, programmed long AVD, prolonged VA conduction time caused by anti-arrhythmic medication, and the rate of ELT (110bpm, below the upper tracking rate of 120bpm) were the reason ELT continued even in the presence of a programmed ELT termination algorithm. Physicians who manage patients with
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br Conclusion Accumulating clinical data suggest the
2019-06-10
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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br Materials and methods br Results br Discussion To
2019-06-10
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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Bone marrow resident Macs Osteomacs are located in canopy
2019-06-10
Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow egfr pathway and they d
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Of note gender equity might continue despite the economic de
2019-06-06
Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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Declaration of interests br Abstract Background In
2019-06-06
Declaration of interests Abstract Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds and shallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes to overall sodium intake. Altho
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There are limitations to the current study
2019-06-06
There are limitations to the current study. As with all surveys, there is an inherent bias in those that are contacted and in those that respond. Obtaining 90 responses on this topic is clearly important, however, the study would be strengthened by a greater number of responses. In addition, the maj
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A quadripolar mapping catheter was placed
2019-06-06
A quadripolar mapping catheter was placed along the RV septum, and a 3.5mm bidirectional open irrigated mapping catheter (ThermoChool SF®, Biosense Webster, Johnson׳s & Johnson׳s, Diamond Bar, CA, US) was inserted retrogradely into the LV. An electroanatomical substrate map created using the CARTO3®
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Como ha destacado Leonardo Tarife o su
2019-06-06
Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac
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Even with the limitations in the available data
2019-06-06
Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of
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Para garantizar la aplicaci n y permanencia de las reformas
2019-06-06
Para garantizar la aplicación y permanencia de las reformas emprendidas, se necesitaba de un marco normativo institucional que brindara estabilidad al modelo, emitiendo señales de confianza al capital transnacional y otros actores privados que invertían en Perú. La Constitución de 1993, elaborada po
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Un a o despu s como
2019-06-06
Un año después, como parte del influjo posconciliar, fue publicada la encíclica del papa Pablo vi, quien presidió su papado de 1963-1978, Populorum Progressio (1967). La novedad de este documento de enseñanza social católica fue la insinuación de una fuerte crítica hacia el orden económico internaci
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lipid metabolism br Universalismo cosmopolitismo y pol ticas
2019-06-06
Universalismo, cosmopolitismo y políticas culturales La conciencia universalista y el cosmopolitismo han sido productos de los movimientos y de los intercambios cada vez más acelerados de nuestro mundo. Desde las expansiones mercantiles y católicas del siglo xvi, los parámetros y los referentes a
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