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We observed a downregulation of
2019-06-19
We observed a downregulation of several thyroid-related genes such as DUOX1, DUOX2, TG, and TSHR. This may appear counterintuitive given that dedifferentiation typically worsens patient outcomes. However, it is noteworthy that there was no difference in the pyk2 of SLC5A5 (sodium-iodide symporter),
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Numerous clinical trials phase II and phase
2019-06-19
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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Your support for the official journal of the
2019-06-19
Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces
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AC regimens have also demonstrated better preventive effects
2019-06-19
AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst
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En el segundo grupo se ubican los
2019-06-19
En el segundo grupo se ubican los pueblos indígenas y comunidades afectadas por la industria extractiva, los mismos que han protagonizado intensas y masivas protestas en puntos tan disímiles del territorio nacional como Cajamarca, Arequipa, Piura o la Amazonía. Se trata de diversas poblaciones que o
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Outra implica o envolvida com as os e que
2019-06-19
Outra implicação envolvida com as os e que tem sido uma das principais bandeiras levantada por entidades contrárias é elastase inhibitor considerada terceirização da saúde pública. A terceirização foi assumida por alguns agentes envolvidos no processo, como o ex-secretário de saúde paulista e sanita
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br Disclosures br Acknowledgments This study was supported b
2019-06-19
Disclosures Acknowledgments This study was supported by the Austrian National Science Fund (FWF), Grant # SFB-F4704. Introduction Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Extramedullary involvement of the kidneys is seen in around 7% when assessed by in
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Efforts to estimate the global burden of typhoid fever can
2019-06-18
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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The results of the study are highly encouraging
2019-06-18
The results of the study are highly encouraging. HIV testing rates were significantly higher in the intervention arm than in the control arm (92% 55%). In multivariable models, the likelihood of not receiving an HIV test was more than 11-fold greater (adjusted odds ratio 11·2, 95% CI 8·8–14·3; pand
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Sendo o propositor da lei das
2019-06-18
Sendo o propositor da lei das os, Bresser Pereira as definiu como entidades sem fim lucrativo, públicas não estatais, financiadas pelo Estado e por ele controladas através de contrato de gestão com fxação de indicadores de desempenho. Dessa forma proporcionariam maior autonomia e flexibilidade das a
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purchase ISO-1 El estudio se realiza desde una
2019-06-18
El estudio se realiza desde una perspectiva cualitativa, purchase ISO-1 partir del análisis del discurso de entrevistas a miembros de los movimientos sociales, así como de declaraciones, discursos y otros textos vinculados tanto a gobiernos, como a los movimientos y sus respectivos proyectos y espac
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br TIEMPO DE CAMBIOS LA REINVENCI N IDENTITARIA
2019-06-18
TIEMPO DE CAMBIOS: LA REINVENCIÓN IDENTITARIA DE DOS FELIGRESÍAS INDÍGENAS Hemos tenido ocasión de exponer que, en la capital mexicana, el tlaxilacalli de Acatla se habría favorecido notablemente del proceso de secularización de la parcialidad de San Pablo, que el arzobispo Montúfar condujo Azimi
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Por ejemplo se encuentran art
2019-06-18
Por ejemplo, se encuentran artículos que analizan los sistemas curriculares, la didáctica empleada en la enseñanza, la formación de profesores, la pedagogía implementada en las clases, la educación en valores, entre otros. Se destacan varios trabajos que proyectan las reflexiones morinianas en el co
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br For more than a decade WHO has focused its
2019-06-18
For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor
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br Discussion Prehabilitation is a program to enhance
2019-06-18
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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