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Both numerical and experimental studies have shown
2018-10-24
Both numerical and experimental studies have shown that gluing the piezoelectric elements onto the beam only insignificantly affects the object\'s natural frequencies and eigenmodes. This allowed to generate a calculated estimation of the modal matrices based on the data obtained: Next, the modal
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The use of good quality instruments is necessary when
2018-10-24
The use of good quality instruments is necessary when examining associations between adolescents’ neighbourhood social environments and their health and well-being. Different approaches are taken to conceptualisation, operationalisation and measurement which might explain inconsistent research findi
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Interestingly in their simulation model Lodding and colleagu
2018-10-23
Interestingly, in their simulation model, Lodding and colleagues were able to predict their real rate of recipients with a high CMV viral load (1.4%, arbitrarily set at >18,200IU/mL) with the assumption of their lower doubling time of 4.3days. Using a shorter doubling time of 1.3days, the proportion
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Our study shows that the gut
2018-10-23
Our study shows that the gut microbiota in both genetic and simple obesity share similar structural and functional features of dysbiosis, such as 1) higher production of toxins with known potential to induce metabolic deteriorations such as TMAO and indoxyl sulfate; 2) higher abundance of genomes th
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We also identified a peak in the Chr p next
2018-10-23
We also identified a peak in the Chr8p23.1 next to HMGB1P46 when analysing the male only dataset, and the P value of the top SNP rs6986153 was 8.02×10 with an OR of 1.67. HMGB1P46 is a pseudogene of high mobility group box-1 (HMGB1). It is suggested that the induction of high mobility group box-1 in
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Our recent study comparing clinical parameters
2018-10-23
Our recent study comparing clinical parameters and K+ transport in red molecular mass calculator from HbSS and HbSC patients indicated significant differences between the two genotypes (Rees et al., 2015). In particular, KCC activity was higher in HbSC patients with more severe forms of SCD (Rees e
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dihydrofolate reductase inhibitor antibacterial The lack of
2018-10-23
The lack of such stratification may underlie the inconsistent data from trials of LMWH for PMPC (Martinelli et al., 2012; Rodger et al., 2014) due to inclusion of heterogeneous disease mechanisms rather than a focus on those associated with a procoagulant mechanism. These findings also suggest that
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The ZIKV field is still developing and critics regarding the
2018-10-23
The ZIKV field is still developing, and critics regarding the use of the original ZIKV strain are starting to emerge. There is currently no appropriate African and Asian reference strains to allow proper comparison of results between laboratories. At this stage, we cannot disregard that the differen
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q vd oph Another limitation of this study
2018-10-23
Another limitation of this study relates to how metabolic change in response to fasting differs among species. For example, in a recent report, lipidomic analysis of human and animal plasma showed that lipid metabolism differed markedly between humans and rats during fasting (Ishikawa et al., 2015).
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Metabonomic alterations as a result
2018-10-23
Metabonomic alterations as a result of antibiotic use are important in the context of CDI (Theriot et al., 2014). As an example, primary and secondary bile acids have markedly different effects on C. difficile; primary bile acids promote growth of this pathogen while secondary bile acids are inhibi
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EHop-016 Supplier In the present study we
2018-10-23
In the present study, we show that IL-10 and Rag1 double knockout mice (IL-10−/−/Rag1−/−) spontaneously develop colitis with high levels of M1 macrophage signature molecules, suggesting that IL-10 regulated M1 macrophages may contribute to the colitis development. We demonstrate that IL-10 or LPS st
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It has been known for
2018-10-23
It has been known for some 30years now that manifest autoimmune disease is correlated with changes in the glycosylation of antibodies (), and the list of autoimmune diseases with alteration in IgG glycosylation is rapidly growing with increasingly detailed analysis of glycoforms (for a review see ()
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Developing an Artificial Bacterial Consortium to Modulate Mi
2018-10-23
Developing an Artificial Bacterial Consortium to Modulate Microbiota of Frail Elderly The microbial composition of the gut changes gradually with aging and is influenced by habitual diet and health status. In one cohort studied, frail elderly had a microbiota profile characterized by an increase i
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A successful vaccine should lead to the generation
2018-10-23
A successful vaccine should lead to the generation of long-lived plasma cells and memory B cells that are thought to be essential for sustained humoral immunity. However, during chronic infection, the persistence of viral mitotic inhibitors alters B cell differentiation into memory cells (Colineau e
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A-443654 br Discussion In the context of
2018-10-23
Discussion In the context of managing diabetes foot infections from an infectious disease viewpoint, current guidelines based on culture-dependent data, are now subject to the scrutiny of molecular DNA based approaches. Furthermore, studies employing amplification and sequence analysis of the 16S
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