• br Data br Experimental design materials and methods br Ackn

  2018-11-07

  

  Data Experimental design, materials and methods Acknowledgements Data Silk fibroin is a natural fibrous protein with advantages for protein loading and delivery in vitro and vivo. However, presumably because of the super-negative charge of fibroin, the application of intracellular delive

• One explanation of the small learning

  2018-11-07

  

  One explanation of the small learning effects of free writing in our study is that the task of writing Chinese characters is more cognitive-resource consuming than writing a letter. Writing characters involves greater demands on visual-spatial working memory, and writing ability itself is constraine

• order AEBSF br Introduction Adolescence is a unique developm

  2018-11-07

  

  Introduction Adolescence is a unique developmental period characterized by major physiological, psychological, and neurodevelopmental changes. These changes typically coincide with escalation of alcohol and marijuana use (Brown et al., 2008), which continues into early adulthood (Sartor et al., 2

• Research into the use of handedness

  2018-11-07

  

  Research into the use of handedness as an indirect measure for speech laterality has formerly proved weak and inconclusive (Groen et al., 2013), predominately due to the variability of methodologies, and hand preference and skill definitions being highly dependent on the measurement and classificati

• This model is supported by

  2018-11-07

  

  This model is supported by several studies demonstrating the impact of alexithymia on socio-cognitive ability, particularly in the affective domain, in both typical and atypical populations. A large body of research demonstrates that alexithymia impairs emotion recognition from both facial (Grynberg

• br Author contributions br Financial disclosures This resear

  2018-11-07

  

  Author contributions Financial disclosures This research was supported by a grant from the Fuller Theological Seminary/Thrive Center in concert with the John Templeton Foundation awarded to J.H.D. and J.S.M.. H.S.S. was supported by a National Science Foundation Graduate Research Fellowship (N

• Second we predicted that autistic

  2018-11-07

  

  Second, we predicted that autistic children should perform better than typical children in Task 3, identifying emotional morphs that had been previously presented to them. This advantage could be due to a greater reliance upon detailed representations of individual items, which are more important in

• MGMT promoter methylation is an important prognostic

  2018-11-06

  

  MGMT promoter methylation is an important prognostic factor for glioma. Patients with methylated-MGMT tumors had a greater chance of responding to adjuvant therapy and a more favorable clinical outcome. In the second specimen of our case, the unmethylated-MGMT increased from 50% to 70%; the MIB-1 in

• The surgical technique was based on that described in a

  2018-11-06

  

  The surgical technique was based on that described in a previous publication. Under general anesthesia, the patient was placed in the supine position with the neck slightly extended. A 5-mm, 30° endoscope with two additional working ports was used for the surgery. The right internal jugular vein was

• br Conclusions Momordica species may be

  2018-11-06

  

  Conclusions Momordica species may be considered as a nutritious vegetable and can play a role in health improving attributes of their wide range of functional components. The green fruits, order GSK-3 Inhibitor IX and stems were rich sources of triterpenoids, carotenoids, phenolics that could po

• Xanthone compounds are natural antioxidants rich in mangoste

  2018-11-06

  

  Xanthone compounds are natural antioxidants rich in mangosteen. Xanthones have effects on neuroprotection, anti-inflammation, anti-oxidative stress and anti-DNA damage. It was reported that the mangosteen extract can execute the protective function on DNA damage through scavenging OH and DPPH free r

• The current study has investigated the cell death pathway s

  2018-11-06

  

  The current study has investigated the cell death pathway(s) utilized by mESCs in response to etoposide (ETO), a topoisomerase II poison that indirectly induces DNA double strand breaks (DSBs) (Baldwin and Osheroff, 2005). The data show that ETO not only induces cell death with hallmarks of both PCD

• The most well studied angiogenic factor that is regulated by

  2018-11-06

  

  The most well-studied angiogenic factor that is regulated by hypoxia is VEGF; hypoxic induction of an HIF-1-dependent bFGF autocrine loop drives angiogenesis, over-expression of Ang-1 causes a significant increase in HIF-1 stabilization and PDGF-BB participates in an autocrine-paracrine survival pat

• Recently our group elucidated the

  2018-11-06

  

  Recently, our group elucidated the role of the endothelium and secretion of angiocrine factors in the expansion of mouse and human HSCs (Butler et al., 2010a, 2010b; Kobayashi et al., 2010). We developed a model of endothelial histone demethylase with autonomous Akt-activation (HUVECs-E4ORF1, referr

• Compared to the adherent monolayer culture

  2018-11-06

  

  Compared to the adherent monolayer culture, an alternative method using suspension culture has been shown to be more effective in obtaining and maintaining the early neural 4EGI-1 emerged during multi-staged differentiation process. Using serum-free medium supplemented with epidermal growth factor

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