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Moreover the here reported results support
2018-10-25
Moreover, the here reported results support the hypothesis that TP53 is not a prognostic but purely predictive type of biomarker (Pilat et al., 2015). A purely predictive marker is considered to affect survival only in the presence of a treatment. In the absence of a treatment or a treatment effect,
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br According to the National Brain
2018-10-25
According to the National Brain Tumor Society, over 120 different types of human herpes simplex virus 1 tumors have been described, the most common of which are gliomas arising from glial (supportive) cells. Approximately two-thirds of brain tumors are benign, but about one third are malignant. T
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Three key factors were considered for selecting catchment ar
2018-10-25
Three key factors were considered for selecting catchment areas from a topographic map that were suitable for harnessing hydropower. The key factors were Senexin B demand, accessibility and river profile. The catchment areas topographies were studied for determining the appropriate elevation for he
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br Acknowledgements The authors are grateful to
2018-10-25
Acknowledgements The authors are grateful to Bushehr University of Medical Sciences for their financial support (Grant no 20/71/1864) and the laboratory staff of the Environmental Health Engineering Department for their cooperation. Specifications Table Value of Data Data Based on the f
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Previous studies have shown that peripheral growth factors s
2018-10-25
Previous studies have shown that peripheral growth factors, such as basic epidermal growth factor, and treatments affecting peripheral cytokines can induce adult ras inhibitor neurogenesis and neuroprotection, as these molecules can cross the blood brain barrier and stimulate mitosis. Therefore, i
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The lineage of differentiation is uncertain Nerve sheath and
2018-10-25
The lineage of differentiation is uncertain. Nerve sheath and cartilaginous origin were commonly suggested differentiation types according to some immunohistochemical and ultrastructural studies, but are still not conclusively proven. All typical OFMT are immunoreactive for vimentin (100%), and 94%
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Topical medications including topical corticosteroid vitamin
2018-10-25
Topical medications including topical corticosteroid, vitamin D3 analogs, and anthralin had been used as adjunctive therapies in patients receiving etanercept for psoriasis treatment. In the present study, all patients did not receive systemic medication or phototherapy as a concomitant treatment. T
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br Acknowledgments This work was supported by the
2018-10-25
Acknowledgments This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean Government (Ministry of Science, ICT, and Future Planning; MSIP) 2011-0028962. Introduction Animal models of vitiligo that develop spontaneously Several animal species repo
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A m lo que m
2018-10-25
A mí lo que más me intriga en esta disputa es por qué el fantasma de la violencia sexual sigue siendo un vehículo cultural de tal eficacia. El abolicionismo se alimenta del espectro de la violencia sexualizada, y vale la pena explorar el abuso que las feministas están haciendo de la figura de la víc
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Una de las grandes consecuencias de la II
2018-10-25
Una de las grandes consecuencias de la II Guerra Mundial fue la ulterior Declaración Universal de Derechos Humanos, desarrollada y escrita por profesores, abogados y políticos, muchos de ellos latinoamericanos. Esta acción ha inspirado una agenda global de derechos humanos y ha creado una plataforma
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br Material and methods br
2018-10-24
Material and methods Acknowledgement We thank Jane Hagelskjær Knudsen, Christian Knudsen, and Bettina Hansen for excellent technical assistance. This project was supported by Aarhus University and partially by the Lundbeck Foundation (R151-2013-14439) and Danish Council for Independent Researc
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Previously we succeeded in visualizing the DNA
2018-10-24
Previously, we succeeded in visualizing the DNA methylation status by injecting a GFP-fused MBD of MBD1 protein (EGFP-MBD-NLS) mRNA into living mice zygotes. Using this method, we visualized the DNA methylation dynamics in preimplantation mouse embryos and found that DNA hypomethylation of major and
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br Experimental Procedures br Acknowledgments
2018-10-24
Experimental Procedures Acknowledgments Introduction New neurons are continuously generated in the hippocampal dentate gyrus (DG) throughout life in mammals, including rodents (Altman and Das, 1965; Kaplan and Hinds, 1977; Kuhn et al., 1996), nonhuman primates (Gould et al., 1999; Kornack a
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One of these factors SWI SNF
2018-10-24
One of these factors, SWI/SNF, is a large chromatin-remodeling complex that contains either BRG1 or BRM exclusively as the catalytic ATPase subunit that drives the alteration of DNA-nucleosome structure and thus regulates gene transcription (Fryer and Archer, 1998; Trotter and Archer, 2008; Wang et
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There are three possible explanations for our
2018-10-24
There are three possible explanations for our findings. First, it is possible that the reprogramming process resulted in iPSCs that were solely derived from methylated FM fibroblasts and not of the unmethylated cells. This assumes that methylated FM fibroblasts were present in our culture, which acc
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