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The quality of each paper was depicted by
2018-11-07
The quality of each paper was depicted by a score summarising the metrics to provide an overall impression of the quality of the available evidence. A weighting system was employed whereby the score for each metric was divided by the maximum possible value so that each metric had the same weighting
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Despite its benefits as a powerful form of communication
2018-11-07
Despite its benefits as a powerful form of communication (see Barker & Gower, 2010; Hegarty, 2011, p. 95; Smith, 2011, p. 27), the fact is that stories remain a largely unconventional means of brand communication (Barker & Gower, 2010). In the III National Conference of Retail that took place in Bar
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Merimepodib The fluoroquinolone group gemifloxacin is one
2018-11-07
The fluoroquinolone group (gemifloxacin) is one of the most important pharmaceuticals used universal wide for humans and veterinary purposes. The occurrence of broad-spectrum antibiotics similar to these in aquatic environments may approach serious threats to the ecosystem and human health by making
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Adan and Natale in a study
2018-11-07
Adan and Natale (2002), in a study conducted in Barcelona involving 2135 individuals with age between 17 and 30 years, verified association between the male gender and eveningness [40]. In the same year, in Brazil, Hidalgo et al. (2003) investigated 318 individuals of the same age, obtaining the sam
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Un primer indicador para la formaci
2018-11-07
Un primer indicador para la formación de coaliciones es la definición de las preferencias de los legisladores, asociadas a los intereses partidistas. Preferencias de los principales jugadores partidarios La fracción parlamentaria del pan en la Cámara de Diputados y Senadores asumió la posición d
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The protocol for blood specimen procurement was
2018-11-07
The protocol for blood specimen procurement was approved by the Institutional Review Board of Thomas Jefferson University. Seventeen UM patients, including ten patients who had liver only metastasis and seven patients who had hepatic and extra-hepatic metastases, were enrolled in this study between
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TGF sign http www apexbt com media diy images wb
2018-11-07
TGF-β signaling is critical for differentiation and survival of SMCs from NCSCs and for maintaining the contractile phenotype late in life (Humphrey et al., 2014; Mao et al., 2012; Xie et al., 2013). In NCSCs, p-Smad2 interacts with the myocardin-related transcription factor to regulate SMC marker g
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Of the two GWA studies
2018-11-07
Of the two GWA studies related to sepsis reported so far (Man et al., 2013; Rautanen et al., 2015) the former focused on treatment response in 1446 patients with (severe) sepsis while the latter was aiming on 28day mortality in 1533 patients with sepsis due to pneumonia. Both GWAS used the consensus
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HNP is the most abundant granule protein in neutrophils Whil
2018-11-07
HNP1 is the most abundant granule protein in neutrophils. While neutrophils have previously been found to be pro-atherogenic by instructing monocyte recruitment (Drechsler et al., 2010; Döring et al., 2012), the here presented data may seemingly suggest an opposite effect. However, rather than attri
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In the present study in vivo leptin treatment
2018-11-07
In the present study, in vivo leptin treatment induced the phosphorylation of STAT3 in neurons and astrocytes but not in microglia, whereas it did not affect inflammation induced by TNFα in hypothalamic cultures (Pan et al., 2008; Wang et al., 2015). Consistent with our findings, it is demonstrated
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TC-G 1000 The endocannabinoid system ECS is a recently emer
2018-11-07
The endocannabinoid system (ECS) is a recently emerging complex regulator of multiple physiological processes. It comprises several endogenous ligands (e.g. -arachidonoylethanolamine, a.k.a. anandamide [AEA], 2-arachidonoylglycerol [2-AG], palmitoylethanolamide [PEA], etc.), a number of endocannabin
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Pls are a special class
2018-11-07
Pls are a special class of glycerophospholipids characterized by a vinyl ether bond at the sn-1 position of glycerol backbone, and they are sometimes called plasmenyl phospholipid or alkenyl acryl phospholipid. They are found in almost all mammalian tissues and constitute about 18–20% of the total p
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The CDKN A gene locus encodes
2018-11-07
The CDKN2A gene locus encodes for p14ARF, p16INK4a, and the long non-coding RNA ANRIL, which negatively regulates p16INK4a. p16INK4a inhibits CDK4 and CDK6 activity, which regulate the RB-E2F axis and cell cycle progression (Nilsson and Landberg, 2006; Jin et al., 1995; Jacobs et al., 1999; Abella e
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The label free quantitative proteomic
2018-11-07
The label-free quantitative proteomic analysis was performed using Normalized Spectral Index (SI) based on the previous description [3,4]. This label-free quantitative value, SI, consists of multiple MS abundance features for a given protein hit: peptide count, spectral count for all assigned peptid
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Further we sort the lipids into annular and
2018-11-07
Further, we sort the palmitic acid into annular and non-annual regions (Fig. 12). Finally, we plot the lipid-number mismatch and surface area per lipid mismatch of several asymmetric lipid membrane systems (Fig. 13). The design of the initial structures (Fig. 8) of the dimer protein and lipid bilay
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