• br Role of dysfunctional telomeres in

  2019-04-19

  

  Role of dysfunctional telomeres in activation of p38 MAPK pathway as response to genotoxic stress Telomeres are unique structures at the ends of chromosomes that are located adjacent to more gene rich sub-telomeric regions and comprised of tandem GT-rich repeats, (TTAGGG)n in humans and other ve

• nadph oxidase inhibitor Pain flare defined as a temporary wo

  2019-04-19

  

  Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte

• The exact incidences of amiodarone induced hyperthyroidism a

  2019-04-19

  

  The exact incidences of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism currently remain unknown; however, the reported frequencies of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism vary widely from 0.8% to 37.8% [7–16] and from 1% to 32% [13,17–20]

• Tambi n debemos tener presente el horizonte en

  2019-04-19

  

  También debemos tener presente el horizonte en el que se inscriben colecciones como la aquí revisada. Si aceptamos que nos encontramos bajo un panorama de fragmentación del conocimiento y segmentación de las disciplinas, se muestra fundamental la recuperación de la toma de partida por la cultura, en

• En el segundo grupo se ubican los

  2019-04-19

  

  En el segundo grupo se ubican los pueblos indígenas y comunidades afectadas por la industria extractiva, los mismos que han protagonizado intensas y masivas protestas en puntos tan disímiles del territorio nacional como Cajamarca, Arequipa, Piura o la Amazonía. Se trata de diversas poblaciones que o

• The NKG D NKG DL system has an important role

  2019-04-18

  

  The NKG2D/NKG2DL system has an important role in tumor immune surveillance, and the NKG2D-activating receptor is expressed in various immune cells, including NK cells, NK T cells, and CD8+ T cells. MICA is one of the NKG2D ligands and is rarely expressed on healthy cells; however, its expression may

• Clearly there are limitations to the current

  2019-04-18

  

  Clearly there are limitations to the current study. These include the single centre, retrospective nature of the study as well as its relatively small sample size compared with the randomised data. However, the duration of follow up is considerably longer than these trials (Table 1). In conclusion,

• In Jillian Pintye and colleagues from

  2019-04-18

  

  In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were

• In this context in Heather Zar and

  2019-04-17

  

  In this context, in , Heather Zar and colleagues report findings from the first study to assess the accuracy of Xpert MTB/RIF in young children presenting to a primary-care facility with symptoms of pulmonary tuberculosis. Primary analysis was done in 309 children in whom four samples (two induced s

• Worldwide one in three women experience gender based violenc

  2019-04-17

  

  Worldwide, one in three women experience gender-based violence, which imparts physical, mental, and sexual health morbidities. It also causes mortality—more than a third of homicides of women are attributable to male partners. These data justifiably create global outrage, accentuated by horrific rec

• TAPI-1 This week the global health cynosure has been the Wor

  2019-04-17

  

  This week the global health cynosure has been the World Health Assembly (WHA) in Geneva. On the agenda we\'ve seen action plans galore: from tuberculosis control to disability to neonatal health. There have been follow-up reports on vaccination, non-communicable diseases, and nutrition. But one thin

• Paraguay es puntual en la redacci n

  2019-04-17

  

  Paraguay es puntual en la redacción del Artículo 8 de su Constitución Nacional cuando dice que “Las actividades susceptibles de producir alteración ambiental serán reguladas por la ley. Asimismo, ésta podrá restringir o prohibir aquéllas que califique peligrosas”. Describe allí las actividades que p

• im 12 En este proceso de integraci n y unidad

  2019-04-17

  

  En este proceso de integración y unidad latinoamericana y caribeña, la imagen política y diplomática de Estados Unidos se vio seriamente mermada por su terrible campaña contra el terrorismo. Su economía se mantiene sumergida en una aguda crisis financiera desde 2008, la más profunda desde 1929. A pe

• Osteoporosis was defined as BMD standard deviations or more

  2019-04-17

  

  Osteoporosis was defined as BMD 2.5 standard deviations or more below the reference range mean for young adults. Osteopaenia being those with a BMD between 1 and 2.5 standard deviations below the young adult mean [7]. Lumbar spine (L2-L4) and femoral neck BMD was quantified with Lunar DPX-L (Lunar,

• Los antecedentes que en este sentido se agradecen son las

  2019-04-17

  

  Los antecedentes que en este sentido se agradecen son las referencias a los géneros —forense y epidíptico— que convergen en los discursos de quienes presenciaron los acontecimientos de la Conquista. Herencias del medioevo: la tradición bíblica, fábulas y el imaginario pagano, detrás de los que exist

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