• Pain flare defined as a temporary worsening of bone pain

  2019-05-23

  

  Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte

• Por sua vez na Nicar gua

  2019-05-23

  

  Por sua vez, na Nicarágua, Go 6983 Revolução Sandinista de 1979 foi resultado de um acúmulo de forças sociais heterogêneas –camponeses, operários, pobres e marginalizados da cidade e do campo, intelectuais e setores progressistas da burguesia– em torno de um objetivo comum: liquidar o governo da fa

• One of the unheralded developments in global health

  2019-05-23

  

  One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.

• Juan Tovar dramaturgo y cr tico teatral presenta en

  2019-05-23

  

  Juan Tovar, dramaturgo y crítico teatral presenta en su texto “Los siete géneros”, la teoría que aprendió durante su paso por las aulas de la maestra Luisa Josefina Hernández y cuyas lecciones no obstante su continuo estudio y aplicación por directores y actores en talleres y escuelas de teatro, no

• The occurrence of RNRVAS first reported as

  2019-05-23

  

  The occurrence of RNRVAS, first reported as an isolated case in 1985 [16], have since been confirmed in dual-chamber pacemaker recipients undergoing 24-h ambulatory electrocardiograms, who report symptoms similar to those of patients suffering from pacemaker syndrome [17,18]. Incidence of RNRVAS

• br Introduction Despite the widespread

  2019-05-23

  

  Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested

• Worldwide there are an estimated

  2019-05-23

  

  Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,

• Since the progressive introduction of the

  2019-05-22

  

  Since the progressive introduction of the meningococcal serogroup A conjugate vaccine in meningitis belt countries via mass vaccination campaigns of 1–29 year olds starting in 2010, a remarkable effect of the vaccine has been observed. Similar to other conjugate vaccines, MenAfriVac has demonstrated

• br Conclusions br Disclosures br Introduction Since their in

  2019-05-22

  

  Conclusions Disclosures Introduction Since their introduction, at the end of fifties, cardiovascular implantable devices (CIEDs) have widely expanded in number and in their functions [1,2]. The dramatic increase in the number of CIEDs implanted in the last decade is mainly due to the aging

• br Conclusion br Conflict of

  2019-05-22

  

  Conclusion Conflict of interest Introduction Radiofrequency catheter ablation has been established as an effective and curative therapy for Wolff-Parkinson-White Syndrome [1–4]. Therefore, prediction of the precise location of an accessory pathway (AP) prior to the ablation procedure is of

• br Conflict of interest br Acknowledgments br

  2019-05-22

  

  Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide Senexin B pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome expres

• Stigma and discrimination experienced by sex workers injecti

  2019-05-22

  

  Stigma and discrimination experienced by sex workers, injection drug users, and men who have sex with men is tough to tackle. Responses need to be tailored to very different circumstances and require interventions on several levels: policy, societal, health system, and individual. There is no magic

• nitric oxide synthase inhibitor Introduction Myelodysplastic

  2019-05-22

  

  Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal

• We moreover confirmed previous evidence of a net

  2019-05-22

  

  We, moreover, confirmed previous evidence of a net increase of CT density of bone metastases after ZA treatment and demonstrated that the changes persist at a 24 months follow-up. This study and previous reports [24–26] have demonstrated significant sclerotic changes of BMs, more evident in patients

• Avasimibe br Vascular cells and the peribiliary vascular ple

  2019-05-22

  

  Vascular cells and the peribiliary vascular plexus The liver is a highly vascularized organ that receives dual blood supplies from the hepatic portal vein (HPV) and hepatic Avasimibe (Fig. 1). The HPV delivers approximately 75% of the total blood supply that the liver receives and carries from t

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